His life was recorded in the Annals of Lancaster Co, PA:
"In his early days he worked on his father's farm, meantime attending common school and a term at the Lititz Academy, under Professor John Beck. There he mastered English, German text and German script writing."
Rothsville, PA. "He entered the store of Samuel B. Myers as book-keeper, continuing thus for one year, when Mr. Myers sold out and removed to Virginia.
He taught school for three terms, working on the home farm during the summer vacations.
Brunnerville, PA "After his marriage Mr. Wissler intended to farm, but land was so high in price at the time that it was considered unprofitable to buy, and the Brunnerville (the Whitehall) store stand being sold on account of the death of Levi H. Yundt, the proprietor, the latter was purchased by Ezra Wissler, the father, for his son John B. Mr. Wissler rented it from his father until 1877, when circumstances beyond John B. Wissler's control induced his father to give him the deed to the store property. He kept the store from 1858 to 1892, had the Brunnerville post office established in 1861, and held it as postmaster until 1892, when he resigned the office and retired from business, selling his stock of goods to his son-in-law A.E. Lane."
His marriage resulted in 4 children, only 2 daughters lived to adulthood and one of them was still living at home late in life.
His death was the result of gastritis and heart failure after an illness of over four months.